Heparanase Facilitates Cell Adhesion and Spreading by Clustering of Cell Surface Heparan Sulfate Proteoglycans

Heparanase is a heparan sulfate (HS) degrading endoglycosidase participating in extracellular matrix degradation and remodeling. Apart of its well characterized enzymatic activity, heparanase was noted to exert also enzymatic-independent functions. Non-enzymatic activities of heparanase include enha...

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Bibliographic Details
Main Authors: Levy-Adam, Flonia, Feld, Sari, Suss-Toby, Edith, Vlodavsky, Israel, Ilan, Neta
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2405934/
https://ncbi.nlm.nih.gov/pubmed/18545691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002319
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