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Expression in yeast of binding regions of karyopherins α and β inhibits nuclear import and cell growth

Using truncated forms of recombinant yeast karyopherins α and β in in vitro binding assays, we mapped the regions of karyopherin α that bind to karyopherin β and the regions of karyopherin β that interact with karyopherin α and with Ran-GTP. Karyopherin α’s binding region for karyopherin β was local...

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Bibliographische Detailangaben
Hauptverfasser: Enenkel, Cordula, Schülke, Norbert, Blobel, Günter
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1996
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24033/
https://ncbi.nlm.nih.gov/pubmed/8917531
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