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Karyopherin β2 mediates nuclear import of a mRNA binding protein

We have cloned and sequenced cDNA for human karyopherin β2, also known as transportin. In a solution binding assay, recombinant β2 bound directly to recombinant nuclear mRNA-binding protein A1. Binding was inhibited by a peptide representing A1’s previously characterized M9 nuclear localization sequ...

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Detalhes bibliográficos
Main Authors: Bonifaci, Neris, Moroianu, Junona, Radu, Aurelian, Blobel, Günter
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24630/
https://ncbi.nlm.nih.gov/pubmed/9144189
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