The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence.
By using proteolysis, recombinant mutant proteins, or synthetic peptides and by testing these reagents in liquid phase binding or nuclear import assays, we have mapped binding regions of karyopherin alpha. We found that the C-terminal region of karyopherin alpha recognizes the nuclear localization s...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1996
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39066/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692858/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6572 |
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