The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence.
By using proteolysis, recombinant mutant proteins, or synthetic peptides and by testing these reagents in liquid phase binding or nuclear import assays, we have mapped binding regions of karyopherin alpha. We found that the C-terminal region of karyopherin alpha recognizes the nuclear localization s...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1996
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39066/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692858/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6572 |
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