Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro.
We have probed the structural organization of the human immunodeficiency virus type 1 integrase protein by limited proteolysis and the functional organization by site-directed mutagenesis of selected amino acid residues. A central region of the protein was relatively resistant to proteolysis. Protei...
Gespeichert in:
| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1992
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240128/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1404595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6361-6369.1992 |
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