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Miniaturization of Scorpion β-Toxins Uncovers a Putative Ancestral Surface of Interaction with Voltage-gated Sodium Channels

The bioactive surface of scorpion β-toxins that interact with receptor site-4 at voltage-gated sodium channels is constituted of residues of the conserved βαββ core and the C-tail. In an attempt to evaluate the extent by which residues of the toxin core contribute to bioactivity, the anti-insect and...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cohen, Lior, Lipstein, Noa, Karbat, Izhar, Ilan, Nitza, Gilles, Nicolas, Kahn, Roy, Gordon, Dalia, Gurevitz, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397468/
https://ncbi.nlm.nih.gov/pubmed/18339620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801229200
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