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Healthy Individuals Have Goodpasture Autoantigen-Reactive T Cells

Autoreactive T cells in patients with Goodpasture's disease are specific for epitopes in the Goodpasture antigen (the NC1 domain of the α3 chain of type IV collagen) that are rapidly destroyed during antigen processing to a degree that diminishes their presentation to T cells. We hypothesized t...

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Detalles Bibliográficos
Main Authors: Zou, Juan, Hannier, Sigrid, Cairns, Lindsay S., Barker, Robert N., Rees, Andrew J., Turner, A. Neil, Phelps, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396752/
https://ncbi.nlm.nih.gov/pubmed/18216317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007050546
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