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Healthy Individuals Have Goodpasture Autoantigen-Reactive T Cells

Autoreactive T cells in patients with Goodpasture's disease are specific for epitopes in the Goodpasture antigen (the NC1 domain of the α3 chain of type IV collagen) that are rapidly destroyed during antigen processing to a degree that diminishes their presentation to T cells. We hypothesized t...

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Detalhes bibliográficos
Main Authors: Zou, Juan, Hannier, Sigrid, Cairns, Lindsay S., Barker, Robert N., Rees, Andrew J., Turner, A. Neil, Phelps, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396752/
https://ncbi.nlm.nih.gov/pubmed/18216317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007050546
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