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The N-terminal conformation of Bax regulates cell commitment to apoptosis
The Bcl-2 protein Bax normally resides in the cytosol, but during apoptosis it translocates to mitochondria where it is responsible for releasing apoptogenic factors. Using anoikis as a model, we have shown that Bax translocation does not commit cells to apoptosis, and they can be rescued by reattac...
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| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396387/ https://ncbi.nlm.nih.gov/pubmed/17273174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.cdd.4402092 |
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