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Integrin-Mediated Survival Signals Regulate the Apoptotic Function of Bax through Its Conformation and Subcellular Localization

Most normal cells require adhesion to extracellular matrix for survival, but the molecular mechanisms that link cell surface adhesion events to the intracellular apoptotic machinery are not understood. Bcl-2 family proteins regulate apoptosis induced by a variety of cellular insults through acting o...

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Detalhes bibliográficos
Main Authors: Gilmore, Andrew P., Metcalfe, Anthony D., Romer, Lewis H., Streuli, Charles H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175159/
https://ncbi.nlm.nih.gov/pubmed/10769034
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