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Analysis of endogenous Bax complexes during apoptosis using blue native PAGE - implications for Bax activation and oligomerisation
Bax, a pro-apoptotic Bcl-2 family protein, translocates to mitochondria during apoptosis, where it brings about mitochondrial outer membrane permeabilisation (MOMP). MOMP releases pro-apoptotic factors, such as cytochrome c and SMAC/Diablo, into the cytosol where they activate caspases. It is often...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396388/ https://ncbi.nlm.nih.gov/pubmed/18307410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071548 |
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