IKKα Causes Chromatin Modification on Pro-Inflammatory Genes by Cigarette Smoke in Mouse Lung

Cigarette smoke (CS) induces abnormal and sustained lung inflammation; however, the molecular mechanism underlying sustained inflammation is not known. It is well known that activation of IκB kinase β (IKKβ) leads to transient translocation of active NF-κB (RelA/p65-p50) in the nucleus and transcrip...

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Main Authors: Yang, Se-Ran, Valvo, Samantha, Yao, Hongwei, Kode, Aruna, Rajendrasozhan, Saravanan, Edirisinghe, Indika, Caito, Samuel, Adenuga, David, Henry, Ryan, Fromm, George, Maggirwar, Sanjay, Li, Jian-Dong, Bulger, Michael, Rahman, Irfan
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396248/
https://ncbi.nlm.nih.gov/pubmed/18239189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0379OC
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