Genetic Ablation of NADPH Oxidase Enhances Susceptibility to Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice

Cigarette smoke (CS) induces recruitment of inflammatory cells in the lungs leading to the generation of reactive oxygen species (ROS), which are involved in lung inflammation and injury. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is a multimeric system that is responsible for ROS p...

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Detalhes bibliográficos
Main Authors: Yao, Hongwei, Edirisinghe, Indika, Yang, Se-Ran, Rajendrasozhan, Saravanan, Kode, Aruna, Caito, Samuel, Adenuga, David, Rahman, Irfan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329832/
https://ncbi.nlm.nih.gov/pubmed/18403597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070765
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