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Genetic Ablation of NADPH Oxidase Enhances Susceptibility to Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice

Cigarette smoke (CS) induces recruitment of inflammatory cells in the lungs leading to the generation of reactive oxygen species (ROS), which are involved in lung inflammation and injury. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is a multimeric system that is responsible for ROS p...

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Библиографические подробности
Главные авторы: Yao, Hongwei, Edirisinghe, Indika, Yang, Se-Ran, Rajendrasozhan, Saravanan, Kode, Aruna, Caito, Samuel, Adenuga, David, Rahman, Irfan
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329832/
https://ncbi.nlm.nih.gov/pubmed/18403597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070765
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