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Mrc1, Tof1 and Csm3 inhibit CAG CTG repeat instability by at least two mechanisms

Trinucleotide repeats frequently expand and contract in humans and model organisms. Protein factors that modulate this process have been found by candidate gene approaches or mutant screens for increased expansion rates. To extend this effort, Saccharomyces cerevisiae mutants with higher CAG CTG rep...

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Hlavní autoři: Razidlo, David F., Lahue, Robert S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396238/
https://ncbi.nlm.nih.gov/pubmed/18321795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.01.009
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