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An Alteration of Human Immunodeficiency Virus gp41 Leads to Reduced CCR5 Dependence and CD4 Independence

Human immunodeficiency virus (HIV) type 1 infection requires functional interactions of the viral surface (gp120) glycoprotein with cell surface CD4 and a chemokine coreceptor (usually CCR5 or CXCR4) and of the viral transmembrane (gp41) glycoprotein with the target cell membrane. Extensive genetic...

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Bibliografske podrobnosti
Main Authors: Taylor, Brian M., Foulke, J. Scott, Flinko, Robin, Heredia, Alonso, DeVico, Anthony, Reitz, Marvin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395218/
https://ncbi.nlm.nih.gov/pubmed/18353949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01049-07
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