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Poliovirus 2A(Pro) Increases Viral mRNA and Polysome Stability Coordinately in Time with Cleavage of eIF4G
Poliovirus (PV) 2A protease (2A(Pro)) cleaves eukaryotic initiation factors 4GI and 4GII (eIF4GI and eIF4GII) within virus-infected cells, effectively halting cap-dependent mRNA translation. PV mRNA, which does not possess a 5′ cap, is translated via cap-independent mechanisms within viral protease-...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2395153/ https://ncbi.nlm.nih.gov/pubmed/18400852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01514-07 |
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