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Tumor Antigen LRRC15 Impedes Adenoviral Infection: Implications for Virus-Based Cancer Therapy

Adenoviruses for gene or oncolytic therapy are under development. Notable among these strategies is adenoviral delivery of the tumor suppressor p53. Since all therapeutics have limitations in certain settings, we have undertaken retroviral suppressor screens to identify genes conferring resistance t...

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Detalhes bibliográficos
Main Authors: O'Prey, Jim, Wilkinson, Simon, Ryan, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395123/
https://ncbi.nlm.nih.gov/pubmed/18385238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02273-07
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