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Tumor Antigen LRRC15 Impedes Adenoviral Infection: Implications for Virus-Based Cancer Therapy

Adenoviruses for gene or oncolytic therapy are under development. Notable among these strategies is adenoviral delivery of the tumor suppressor p53. Since all therapeutics have limitations in certain settings, we have undertaken retroviral suppressor screens to identify genes conferring resistance t...

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Bibliographic Details
Main Authors: O'Prey, Jim, Wilkinson, Simon, Ryan, Kevin M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395123/
https://ncbi.nlm.nih.gov/pubmed/18385238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02273-07
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