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TGF-β1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60(c-src)/EGFR(Y845) and Rho/ROCK signaling
TGF-β1 and its target gene encoding plasminogen activator inhibitor-1 (PAI-1) are major causative factors in the pathology of tissue fibrosis and vascular disease. The increasing complexity of TGF-β1 action in the cardiovascular system requires analysis of specific TGF-β1-initiated signaling events...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394714/ https://ncbi.nlm.nih.gov/pubmed/18255094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.12.006 |
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