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High Glucose Oxidizes SERCA Cysteine-674 and Prevents Inhibition by Nitric Oxide of Smooth Muscle Cell Migration
Nitric oxide (NO) causes S-glutathiolation of the reactive cysteine-674 in the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase (SERCA), thus increasing SERCA activity, and inhibiting Ca(2+) influx and migration of vascular smooth muscle cells (VSMC). Because increased VSMC migration contributes to...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394666/ https://ncbi.nlm.nih.gov/pubmed/18164028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.10.022 |
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