Cysteine-674 Oxidation and Degradation of SERCA in Diabetic Pig Aorta

The sarcoplasmic reticulum Ca(2+) ATPase (SERCA) is redox-regulated by post-translational thiol modifications of cysteine-674 to regulate smooth muscle relaxation and migration. To detect oxidation of cysteine-674 that irreversibly prevents redox-regulation, a polyclonal, sequence-specific antibody...

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Hauptverfasser: Ying, Jia, Sharov, Victor, Xu, Shanqin, Jiang, Bingbing, Gerrity, Ross, Schöneich, Christian, Cohen, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654240/
https://ncbi.nlm.nih.gov/pubmed/18590812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.05.029
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