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Bimodal and Hysteretic Expression in Mammalian Cells from a Synthetic Gene Circuit

In order to establish cells and organisms with predictable properties, synthetic biology makes use of controllable, synthetic genetic devices. These devices are used to replace or to interfere with natural pathways. Alternatively, they may be interlinked with endogenous pathways to create artificial...

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Detalhes bibliográficos
Main Authors: May, Tobias, Eccleston, Lee, Herrmann, Sabrina, Hauser, Hansjörg, Goncalves, Jorge, Wirth, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394661/
https://ncbi.nlm.nih.gov/pubmed/18523635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002372
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