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A synthetic mammalian gene circuit reveals antituberculosis compounds
Synthetic biology provides insight into natural gene-network dynamics and enables assembly of engineered transcription circuitries for production of difficult-to-access therapeutic molecules. In Mycobacterium tuberculosis EthR binds to a specific operator (O(ethR)) thereby repressing ethA and preven...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2481315/ https://ncbi.nlm.nih.gov/pubmed/18621677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800663105 |
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