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Transcriptional control of SV40 T-antigen expression allows a complete reversion of immortalization

Conditional proliferation of mouse embryo fibroblasts was achieved with a novel autoregulatory vector for Tet-dependent expression of the SV40 T-antigen. The majority of cell clones that were isolated under induced conditions showed strict regulation of cell growth. Status switches were found to be...

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Hlavní autoři: May, Tobias, Hauser, Hansjörg, Wirth, Dagmar
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC524297/
https://ncbi.nlm.nih.gov/pubmed/15486202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh887
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