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Transcriptional control of SV40 T-antigen expression allows a complete reversion of immortalization
Conditional proliferation of mouse embryo fibroblasts was achieved with a novel autoregulatory vector for Tet-dependent expression of the SV40 T-antigen. The majority of cell clones that were isolated under induced conditions showed strict regulation of cell growth. Status switches were found to be...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524297/ https://ncbi.nlm.nih.gov/pubmed/15486202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh887 |
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