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Mutant Prion Protein D202N Associated with Familial Prion Disease is Retained in the Endoplasmic Reticulum and Forms ‘Curly’ Intracellular Aggregates

Transmissible Spongiform Encephalopathies are fatal neurodegenerative disorders of humans and animals that are familial, sporadic, and infectious in nature. Familial disorders of humans include Gerstmann–Straussler–Scheinker disease (GSS), familial Creutzfeldt–Jakob disease (CJD), and fatal familial...

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Detalhes bibliográficos
Main Authors: Gu, Yaping, Verghese, Susamma, Bose, Sharmila, Mohan, Maradumane, Singh, Neena
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394189/
https://ncbi.nlm.nih.gov/pubmed/17873292
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