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Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms
Endocytosis and subsequent lysosomal degradation serve as a well characterized mechanism to fine-tune and down-regulate EGFR signaling. However, other members of the EGFR/ErbB receptor family have been reported to be endocytosis-impaired. Here we demonstrate that endocytosis of ErbB4 is regulated in...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2393780/ https://ncbi.nlm.nih.gov/pubmed/18334649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708333105 |
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