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Contribution of positively charged flanking residues to the insertion of transmembrane helices into the endoplasmic reticulum
Positively charged residues located near the cytoplasmic end of hydrophobic segments in membrane proteins promote membrane insertion and formation of transmembrane α-helices. A quantitative understanding of this effect has been lacking, however. Here, using an in vitro transcription–translation syst...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2393759/ https://ncbi.nlm.nih.gov/pubmed/18326626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711580105 |
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