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Analysis of the distribution of functionally relevant rare codons
BACKGROUND: The substitution of rare codons with more frequent codons is a commonly applied method in heterologous gene expression to increase protein yields. However, in some cases these substitutions lead to a decrease of protein solubility or activity. To predict these functionally relevant rare...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2391168/ https://ncbi.nlm.nih.gov/pubmed/18457591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-207 |
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