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Network Analysis of Sequence-Function Relationships and Exploration of Sequence Space of TEM β-Lactamases
The Lactamase Engineering Database (www.LacED.uni-stuttgart.de) was developed to facilitate the classification and analysis of TEM β-lactamases. The current version contains 474 TEM variants. Two hundred fifty-nine variants form a large scale-free network of highly connected point mutants. The netwo...
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Publicado no: | Antimicrob Agents Chemother |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862526/ https://ncbi.nlm.nih.gov/pubmed/26883706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02930-15 |
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