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The Isoelectric Region of Proteins: A Systematic Analysis

BACKGROUND: Binding of proteins in ion exchange chromatography is dominated by electrostatic interactions and can be tuned by adjusting pH and ionic strength of the solvent. Therefore, the isoelectric region (IER), the pH region of almost zero charge near the pI, has been used to predict the binding...

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Detalhes bibliográficos
Main Authors: Widmann, Michael, Trodler, Peter, Pleiss, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866324/
https://ncbi.nlm.nih.gov/pubmed/20479870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010546
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