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tPA Protects Renal Interstitial Fibroblasts and Myofibroblasts from Apoptosis
Activation and expansion of interstitial fibroblasts and myofibroblasts play an essential role in the evolution of renal fibrosis. After obstructive injury, mice lacking tissue-type plasminogen activator (tPA) have fewer myofibroblasts and less interstitial fibrosis than wild-type controls. This sug...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Nephrology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2391054/ https://ncbi.nlm.nih.gov/pubmed/18199803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007030300 |
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