tPA Is a Potent Mitogen for Renal Interstitial Fibroblasts : Role of β1 Integrin/Focal Adhesion Kinase Signaling

Proliferation and expansion of interstitial fibroblasts are predominant features of progressive chronic kidney diseases. However, how interstitial fibroblast proliferation is controlled remains ambiguous. Here we show that tissue-type plasminogen activator (tPA) is a potent mitogen that promotes int...

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Detalhes bibliográficos
Main Authors: Hao, Sha, Shen, Hongmei, Hou, Yayi, Mars, Wendy M., Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928951/
https://ncbi.nlm.nih.gov/pubmed/20639453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091269
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