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tPA Is a Potent Mitogen for Renal Interstitial Fibroblasts : Role of β1 Integrin/Focal Adhesion Kinase Signaling
Proliferation and expansion of interstitial fibroblasts are predominant features of progressive chronic kidney diseases. However, how interstitial fibroblast proliferation is controlled remains ambiguous. Here we show that tissue-type plasminogen activator (tPA) is a potent mitogen that promotes int...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Investigative Pathology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928951/ https://ncbi.nlm.nih.gov/pubmed/20639453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091269 |
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