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Inhibition of Integrin-Linked Kinase Attenuates Renal Interstitial Fibrosis

Integrin-linked kinase (ILK) is an intracellular serine/threonine protein kinase that regulates cell adhesion, survival, and epithelial-to-mesenchymal transition (EMT). In this study, we investigated the kinase activity of ILK during tubular EMT induced by TGF-β1 and examined the therapeutic potenti...

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Detalhes bibliográficos
Main Authors: Li, Yingjian, Tan, Xiaoyue, Dai, Chunsun, Stolz, Donna B., Wang, Dan, Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736781/
https://ncbi.nlm.nih.gov/pubmed/19541809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008090930
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