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Inhibition of integrin-linked kinase blocks podocyte epithelial–mesenchymal transition and ameliorates proteinuria

Proteinuria is a primary clinical symptom of a large number of glomerular diseases that progress to end-stage renal failure. Podocyte dysfunctions play a fundamental role in defective glomerular filtration in many common forms of proteinuric kidney disorders. Since binding of these cells to the base...

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Main Authors: Kang, Young Sun, Li, Yingjian, Dai, Chunsun, Kiss, Lawrence P., Wu, Chuanyue, Liu, Youhua
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065782/
https://ncbi.nlm.nih.gov/pubmed/20505657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2010.137
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