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Inhibition of Integrin-Linked Kinase Attenuates Renal Interstitial Fibrosis
Integrin-linked kinase (ILK) is an intracellular serine/threonine protein kinase that regulates cell adhesion, survival, and epithelial-to-mesenchymal transition (EMT). In this study, we investigated the kinase activity of ILK during tubular EMT induced by TGF-β1 and examined the therapeutic potenti...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736781/ https://ncbi.nlm.nih.gov/pubmed/19541809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008090930 |
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