T-bet Deficiency Attenuates Renal Injury in Experimental Crescentic Glomerulonephritis

T-bet is a transcription factor that is essential for T helper (Th)1 lineage commitment and optimal IFN-γ production by CD4(+) T cells. We examined the role of T-bet in the development of experimental crescentic glomerulonephritis, which is induced by Th1-predominant, delayed-type hypersensitivity-l...

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Главные авторы: Phoon, Richard K. S., Kitching, A. Richard, Odobasic, Dragana, Jones, Lynelle K., Semple, Timothy J., Holdsworth, Stephen R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2008
Предметы:
Basic Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391047/
https://ncbi.nlm.nih.gov/pubmed/18235099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007030392
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