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T-bet Deficiency Attenuates Renal Injury in Experimental Crescentic Glomerulonephritis
T-bet is a transcription factor that is essential for T helper (Th)1 lineage commitment and optimal IFN-γ production by CD4(+) T cells. We examined the role of T-bet in the development of experimental crescentic glomerulonephritis, which is induced by Th1-predominant, delayed-type hypersensitivity-l...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Nephrology
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2391047/ https://ncbi.nlm.nih.gov/pubmed/18235099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007030392 |
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