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DcpS scavenger decapping enzyme can modulate pre-mRNA splicing

The human scavenger decapping enzyme, DcpS, functions to hydrolyze the resulting cap structure following cytoplasmic mRNA decay yet is, surprisingly, a nuclear protein by immunofluorescence. Here, we show that DcpS is a nucleocytoplasmic shuttling protein that contains separable nuclear import and C...

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Bibliographic Details
Main Authors: Shen, Vincent, Liu, Hudan, Liu, Shin-Wu, Jiao, Xinfu, Kiledjian, Megerditch
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390800/
https://ncbi.nlm.nih.gov/pubmed/18426921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1008208
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