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Mouse fetal and embryonic liver cells differentiate human umbilical cord blood (UCB) progenitors into CD56 negative NK cell precursors in the absence of IL-15

OBJECTIVE: Human NK cell maturation involves the orderly acquisition of NK cell receptors. Our aim was to understand how stromal interactions and cytokines are important in this developmental process. METHODS: Human UCB CD34(+)/Lin(−)/CD38(−) cells were cultured on two murine stromal cell lines (AFT...

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Detalhes bibliográficos
Main Authors: McCullar, Valarie, Oostendorp, Robert, Panoskaltsis-Mortari, Angela, Yung, Gong, Lutz, Charles T., Wagner, John E., Miller, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390774/
https://ncbi.nlm.nih.gov/pubmed/18295962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2008.01.001
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