Mycolic Acid Modification by the mmaA4 Gene of M. tuberculosis Modulates IL-12 Production

Mycobacterium tuberculosis has evolved many strategies to evade elimination by the host immune system, including the selective repression of macrophage IL-12p40 production. To identify the M. tuberculosis genes responsible for this aspect of immune evasion, we used a macrophage cell line expressing...

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Main Authors: Dao, Dee N., Sweeney, Kari, Hsu, Tsungda, Gurcha, Sudagar S., Nascimento, Ivan P., Roshevsky, Dan, Besra, Gurdyal S., Chan, John, Porcelli, Steven A., Jacobs, William R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390761/
https://ncbi.nlm.nih.gov/pubmed/18535659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000081
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