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Ceramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases

The n-type K(+) channel (n-K(+), K(v)1.3) in lymphocytes has been recently implicated in the regulation of Fas-induced programmed cell death. Here, we demonstrate that ceramide, a lipid metabolite synthesized upon Fas receptor ligation, inhibits n-K(+) channel activity and induces a tyrosine phospho...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gulbins, Erich, Szabo, Ildiko, Baltzer, Katharina, Lang, Florian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC23879/
https://ncbi.nlm.nih.gov/pubmed/9207149
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