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The Tyrosine Kinase p56(lck) Mediates Activation of Swelling-induced Chloride Channels in Lymphocytes
Osmotic cell swelling activates Cl(−) channels to achieve anion efflux. In this study, we find that both the tyrosine kinase inhibitor herbimycin A and genetic knockout of p56(lck), a src-like tyrosine kinase, block regulatory volume decrease (RVD) in a human T cell line. Activation of a swelling-ac...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
1998
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2132720/ https://ncbi.nlm.nih.gov/pubmed/9531565 |
| Oznake: |
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