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A single serine residue controls the cation dependence of substrate transport by the rat serotonin transporter
The serotonin transporter (SERT) is a member of the Na(+)/Cl(−)-dependent neurotransmitter transporter family and constitutes the target of several clinically important antidepressants. Here, replacement of serine-545 in the recombinant rat SERT by alanine was found to alter the cation dependence of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences of the USA
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23875/ https://ncbi.nlm.nih.gov/pubmed/9207145 |
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