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Permeation and gating residues in serotonin transporter

The third transmembrane domain (TM3) of serotonin transporter (SERT) contains two isoleucine residues previously proposed to be involved in binding and transport of serotonin. When Ile-172 was replaced with cysteine, SERT became sensitive to inactivation by externally added [2-(trimethylammonium)eth...

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Autors principals: Chen, Jie-Guang, Rudnick, Gary
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15515/
https://ncbi.nlm.nih.gov/pubmed/10655481
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