Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

The precise identification of the HIV-1 envelope glycoprotein (Env) responsible for productive clinical infection could be instrumental in elucidating the molecular basis of HIV-1 transmission and in designing effective vaccines. Here, we developed a mathematical model of random viral evolution and,...

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Detalhes bibliográficos
Main Authors: Keele, Brandon F., Giorgi, Elena E., Salazar-Gonzalez, Jesus F., Decker, Julie M., Pham, Kimmy T., Salazar, Maria G., Sun, Chuanxi, Grayson, Truman, Wang, Shuyi, Li, Hui, Wei, Xiping, Jiang, Chunlai, Kirchherr, Jennifer L., Gao, Feng, Anderson, Jeffery A., Ping, Li-Hua, Swanstrom, Ronald, Tomaras, Georgia D., Blattner, William A., Goepfert, Paul A., Kilby, J. Michael, Saag, Michael S., Delwart, Eric L., Busch, Michael P., Cohen, Myron S., Montefiori, David C., Haynes, Barton F., Gaschen, Brian, Athreya, Gayathri S., Lee, Ha Y., Wood, Natasha, Seoighe, Cathal, Perelson, Alan S., Bhattacharya, Tanmoy, Korber, Bette T., Hahn, Beatrice H., Shaw, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387184/
https://ncbi.nlm.nih.gov/pubmed/18490657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802203105
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