cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo

Tissue engineering of large bone defects is approached through implantation of autologous osteogenic cells, generally referred to as multipotent stromal cells or mesenchymal stem cells (MSCs). Animal-derived MSCs successfully bridge large bone defects, but models for ectopic bone formation as well a...

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Detalhes bibliográficos
Main Authors: Siddappa, Ramakrishnaiah, Martens, Anton, Doorn, Joyce, Leusink, Anouk, Olivo, Cristina, Licht, Ruud, van Rijn, Linda, Gaspar, Claudia, Fodde, Riccardo, Janssen, Frank, van Blitterswijk, Clemens, de Boer, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387183/
https://ncbi.nlm.nih.gov/pubmed/18490653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711190105
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