Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes

Understanding the mechanisms of multidrug resistance (MDR) could improve clinical drug efficacy. Multidrug resistance is associated with ATP binding cassette (ABC) transporters, but the factors that regulate their expression at clinically relevant drug concentrations are poorly understood. We report...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Calcagno, A M, Fostel, J M, To, K K W, Salcido, C D, Martin, S E, Chewning, K J, Wu, C-P, Varticovski, L, Bates, S E, Caplen, N J, Ambudkar, S V
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386965/
https://ncbi.nlm.nih.gov/pubmed/18382425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604334
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker