Retinoic Acid (RA) Regulates 17β-Hydroxysteroid Dehydrogenase Type 2 Expression in Endometrium: Interaction of RA Receptors with Specificity Protein (SP) 1/SP3 for Estradiol Metabolism

Context: The enzyme 17β-hydroxysteroid dehydrogenase type 2 (HSD17B2) exerts a local antiestrogenic effect by metabolizing biologically active estradiol to inactive estrone in endometrial epithelial cells. Retinoic acid (RA) induces HSD17B2 expression, but the underlying mechanism is not known. Obje...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cheng, You-Hong, Yin, Ping, Xue, Qing, Yilmaz, Bertan, Dawson, Marcia I., Bulun, Serdar E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386682/
https://ncbi.nlm.nih.gov/pubmed/18270252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2007-1536
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados