Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells

Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality in allogeneic stem cell transplantation. Effector memory T cells (T(EM)) do not cause GVHD but engraft and mount immune responses, including graft-versus-tumor effects. One potential explanation for the inability of T(...

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Main Authors: Anderson, Britt E., Taylor, Patricia A., McNiff, Jennifer M., Jain, Dhanpat, Demetris, Anthony J., Panoskaltsis-Mortari, Angela, Ager, Ann, Blazar, Bruce R., Shlomchik, Warren D., Shlomchik, Mark J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Transplantation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384145/
https://ncbi.nlm.nih.gov/pubmed/18285547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-107953
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