Structural and numerical variation of FLT3/ITD in pediatric AML

FLT3 internal tandem duplication (FLT3/ITD) is a common somatic mutation in acute myeloid leukemia (AML) with significant variation in the position, length, and number of duplications of the FLT3 gene. We evaluated these physical characteristics in FLT3/ITD-positive patients who were treated on CCG-...

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Autori principali: Meshinchi, Soheil, Stirewalt, Derek L., Alonzo, Todd A., Boggon, Titus J., Gerbing, Robert B., Rocnik, Jennifer L., Lange, Beverly J., Gilliland, D. Gary, Radich, Jerald P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2008
Soggetti:
Clinical Trials and Observations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384125/
https://ncbi.nlm.nih.gov/pubmed/18305215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-117770
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